Epitome of the Pharmacopeia of the United States and the National Formulary Part 24

=Cimicifuga (Cimicif.), Cimicifuga, U.S.P.= (Black Snake-root, Black Cohosh, Macrotys).--A rhizome.

ACTION AND USES: One of the cla.s.s of "domestic medicines"

that were tried for a great variety of conditions (used as "stomachic, antispasmodic, aphrodisiac, diaph.o.r.etic, diuretic and expectorant"), but which have not been found to possess definite value.

DOSAGE: 1 Gm. or 15 grains (U.S.P.).

_Extractum Cimicifugae (Ext. Cimicif.), Extract of Cimicifuga, U.S.P._ (Powdered Extract of Cimicifuga).--One Gm. extract represents 4 Gm.

cimicifuga.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.).

_Fluidextractum Cimicifuga (Fldext. Cimicif.), Fluidextract of Cimicifuga, U.S.P._ (Fluidextract of Black Cohosh, Fluidextract of Black Snakeroot).--Cimicifuga (100%). Absolute alcohol content about 80 per cent.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

_Syrupus Cimicifugae Compositus (Syr. Cimicif. Co.), Compound Syrup of Cimicifuga, N.F._ (Syrupus Actaeae Compositus, N.F. III, Compound Syrup of Actaea).--Fluidextract of cimicifuga (4%), fluidextract of senega (2%), fluidextract of ipecac (1%), fluidextract of glycyrrhiza, wild cherry, sugar and water. Absolute alcohol content about 5 per cent.

USES: Complex expectorant.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

_Tinctura Cimicifugae (Tr. Cimicif.), Tincture of Cimicifuga, N.F._--Cimicifuga (20%) in alcohol. Absolute alcohol content about 90 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=*Cinchona (Cinch.), Cinchona, U.S.P.= (Yellow Cinchona, Calisaya Bark, Yellow Peruvian Bark).--Yields not less than 5 per cent. of alkaloids.

ACTION AND USES: Astringent bitter tonic.

DOSAGE: 1 Gm. or 15 grains (U.S.P.).

_Elixir Cinchonae Alkaloidorum and Elixir Cinchonae Alkaloidorum et Hypophosphitum._--See under =Quininae Sulphas=.

_Elixir Cinchonae Alkaloidorum et Ferri._--See under =Ferri Phosphas=.

_Elixir Cinchonae Alkaloidorum, Ferri, Bis.m.u.thi et Strychninae and Elixir Cinchonae Alkaloidorum, Ferri et Strychninae._--See under =Strychninae Sulphas=.

_Elixir Cinchonae Alkaloidorum, Ferri et Bis.m.u.thi._--See under =Bis.m.u.thi et Sodii Tartras=.

_Elixir Cinchonae Alkaloidorum, Ferri et Calcii Lactophosphatis._--See under =Calcii Lactophosphas=.

_Elixir Cinchonae Alkaloidorum, Ferri et Pepsini._--See under =Pepsinum=.

_Extractum Cinchonae (Ext. Cinchon.), Extract of Cinchona, N.F._--A hydroalcoholic extract diluted with glucose, yielding about 24 per cent.

of cinchona alkaloids.

DOSAGE: 0.25 Gm. or 4 grains (N.F.).

_Fluidextractum Cinchonae (Fldext. Cinchon.), Fluidextract of Cinchona, U.S.P._--Cinchona (100%) yielding about 4.5 per cent. of alkaloids.

Absolute alcohol content about 65 per cent.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

_Fluidextractum Cinchonae Aquosum (Fldext. Cinchon. Aq.), Aqueous Fluidextract of Cinchona, N.F._--Cinchona (100%), yielding about 5 per cent. of alkaloids. Absolute alcohol content about 12 per cent.

DOSAGE: 1 Cc. or 15 minims (N.F.).

_Infusum Cinchonae (Inf. Cinchon.), Infusion of Cinchona, N.F._--Cinchona (6%), aromatic sulphuric acid (1%) and water.

DOSAGE: 50 Cc. or 12 fluidrachms (N.F.).

_*Tinctura Cinchonae (Tr. Cinch.), Tincture of Cinchona, U.S.P._--Cinchona (20%), yielding about 0.9 per cent. of alkaloids; in alcohol, glycerin and water. Absolute alcohol content about 63 per cent.

DOSAGE: 4 Cc. or 1 fluidrachm (U.S.P.).

=Cinchona Rubra (Cinch. Rub.), Red Cinchona, U.S.P.= (Red Peruvian Bark).--Yields not less than 5 per cent. of alkaloids.

ACTION AND USES: Identical with those of cinchona.

Used as ingredient of the compound tincture of cinchona.

_*Tinctura Cinchonae Composita (Tr. Cinch. Co.), Compound Tincture of Cinchona, U.S.P._--Red cinchona (10%), yielding about 0.45 per cent. of cinchona alkaloids, serpentaria (2%) and bitter orange peel, in glycerin, alcohol and water. Absolute alcohol content about 64 per cent.

USES: Aromatic astringent bitter, of high alcoholic content; superfluous.

DOSAGE: 4 Cc. or 1 fluidrachm (U.S.P.).

=Cinchonidinae Sulphas (Cinchonid. Sulph.), Cinchonidine Sulphate, U.S.P.=--The sulphate of the alkaloid cinchonidine, obtained from cinchona bark.

White, glistening, odorless needles with a very bitter taste.

Soluble in water (1:65) and in alcohol (1:90).

ACTION AND USES: Formerly used as a cheap subst.i.tute for quinine sulphate, over which it possesses no advantage, being less efficient and more convulsant.

DOSAGE: 0.15 Gm. or 2-1/2 grains (U.S.P.).

=Cinchoninae Sulphas (Cinchonin. Sulph.), Cinchonine Sulphate, U.S.P.=--The sulphate of the alkaloid cinchonine, obtained from cinchona bark.

White, l.u.s.trous, odorless crystals with a very bitter taste.

Soluble in water (1:60) and in alcohol (1:12.5).

ACTION AND USES: Similar to those of cinchonidine sulphate.

DOSAGE: 0.15 Gm. or 2-1/2 grains (U.S.P.).