Epitome of the Pharmacopeia of the United States and the National Formulary Part 44

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_*Liquor Hydrogenii Dioxidi (Liq. Hydrog. Diox.), Solution of Hydrogen Dioxide, U.S.P._ (Aqua Hydrogenii Dioxidii, U.S.P. VIII, Solution of Hydrogen Peroxide).--H{2}O{2} (not less than 3%).

ACTION AND USES: Nontoxic and fairly efficient local antiseptic and detergent, useful mainly for the destruction of pus. Used on suppurating wounds and as a mouthwash and gargle; also as a bleaching agent. Should not be injected into a wound unless free drainage is present.

DOSAGE: 4 Cc. or 1 fluidrachm (U.S.P.). For external application should be diluted about 1:4.

=Hyoscyaminae Hydrobromidum (Hyoscyamin. Hydrobr.), Hyoscyamine Hydrobromide, U.S.P.= (Hyoscyamine Bromide).--Obtained from hyoscyamus and other plants of the nightshade family.

White, odorless crystals. Freely soluble in alcohol (1:2.5) and in chloroform (1:1.7); very soluble in water.



ACTION AND USES: Similar to those of atropine; is usually more sedative to the brain, but at times produces acute delirium. The drug is very uncertain.

DOSAGE: 0.3 mg. or 1/200 grain (U.S.P.).

=*Hyoscyamus (Hyosc.), Hyoscyamus, U.S.P.= (Henbane, Hyoscyami Folium, P.I.).--Leaves and tops, yielding not less than 0.065 per cent. of alkaloids.

ACTION AND USES: Similar to those of belladonna.

DOSAGE: 0.25 Gm. or 4 grains (U.S.P.).

_Extractum Hyoscyami (Ext. Hyosc.), Extract of Hyoscyamus, U.S.P._--One Gm. extract represents about 4 Gm. hyoscyamus. Yields about 0.25 per cent. of alkaloids.

DOSAGE: 0.06 Gm. or 1 grain (U.S.P.).

_Fluidextractum Hyoscyami (Fldext. Hyosc.), Fluidextract of Hyoscyamus, U.S.P._ (Fluidextract of Henbane).--Hyoscyamus (100%) yielding about 0.065 per cent. of alkaloids, chiefly hyoscyamine. Absolute alcohol content about 60 per cent.

DOSAGE: 0.2 Cc. or 3 minims (U.S.P.).

_Oleum Hyoscyami Compositum (Ol. Hyosc. Co.), Compound Oil of Hyoscyamus, N.F._ (Balsamum Tranquillans).--Infused oil of hyoscyamus (hyoscyamus 10%) flavored with oils of lavender, peppermint, rosemary and thyme.

_*Tinctura Hyoscyami (Tr. Hyosc.), Tincture of Hyoscyamus, U.S.P._ (Tincture of Henbane, Hyoscyami Tinctura, P.I.).--Hyoscyamus (10%), yielding about 0.0065 per cent. of hyoscyamus alkaloids; in diluted alcohol. Absolute alcohol content about 47 per cent.

DOSAGE: 2 Cc. or 30 minims (U.S.P.).

=*Hypophysis Sicca (Hypophysis Sic.), Desiccated Hypophysis, U.S.P.= (Desiccated Pituitary Body).--The posterior lobe obtained from the pituitary body of cattle.

A yellowish or grayish powder with a characteristic odor. Partially soluble in water.

ACTION AND USES: Solutions are used, hypodermically, to strengthen uterine contractions in prolonged labor. They also stimulate peristalsis and have been used with some success after abdominal operations and as a vasomotor stimulant. Oral administration is ineffective.

DOSAGE: 0.03 Gm. or 1/2 grain (U.S.P.).

_*Liquor Hypophysis (Liq. Hypophysis), Solution of Hypophysis, U.S.P._ (Solution of the Pituitary Body).--Contains the water-soluble principles from the fresh posterior lobe of the pituitary body of cattle. a.s.sayed by testing against a standard solution of beta-iminazolyl-ethylamine hydrochloride by the method of the U.S. Hygienic Laboratory.

DOSAGE: 1 Cc. or 15 minims (U.S.P.).

=Ignatia (Ignat.), Ignatia, N.F.= (Saint Ignatius Bean, Ignatia Amara).--Seeds of _Strychnos ignatii_.

ACTION AND USES: Const.i.tuents and actions similar to those of nux vomica, over which ignatia has no advantage, being less reliable.

DOSAGE: 0.06 Gm. or 1 grain (N.F.).

_Extractum Ignatiae (Ext. Ignat.), Extract of Ignatia, N.F._ (Powdered Extract of Ignatia).--A hydroalcoholic extract, yielding about 6 per cent. of alkaloids.

DOSAGE: 0.03 Gm. or 1/2 grain (N.F.).

_Tinctura Ignatiae (Tr. Ignat.), Tincture of Ignatia, N.F._--Ignatia (10%), yielding about 0.2 per cent. of ignatia alkaloids; in alcohol and water. Absolute alcohol content about 85 per cent.

DOSAGE: 0.6 Cc. or 10 minims (N.F.).

=INFUSA, INFUSIONS.=--Aqueous preparations made by pouring hot or cold water over a vegetable drug, allowing the mixture to stand for a definite period and then straining. For the official infusions, see under the names of the respective drugs.

=Inula (Inula), Inula, N.F.= (Elecampane).--Rhizome and roots.

ACTION AND USES: At one time used in bronchitis. No scientific indications for its use.

DOSAGE: 2 Gm. or 30 grains (N.F.).

=INUNCTA, INUNCTIONS.=--Semisolid ointment-like preparations used for external application. For the various inunctions see under the names of the princ.i.p.al ingredients.

=*Iodoformum (Iodof.), Iodoform, U.S.P.=--Triiodomethane, CHI{3}.

Lemon-yellow powder or l.u.s.trous crystals, with a peculiar, penetrating odor and an unpleasant, slightly sweetish taste suggestive of iodine. Nearly insoluble in water, to which, however, it imparts its odor and taste; soluble in alcohol (1:60) and in glycerin (1:80).

ACTION AND USES: Used as dusting powder, promoting healing by granulation. Oily suspensions are also used in treatment of tuberculous fistulas.

_Collodium Iodoformi (Collod. Iodof.), Iodoform Collodion, N.F._--Iodoform (5%) in flexible collodion.

USES: There appears to be no advantage in applying iodoform in collodion.

_Glycerogelatinum Iodoformi (Glycerogel. Iodof.), Iodoform Glycerogelatin, N.F._--Iodoform (10%), water, glycerin and glycerinated gelatin.

_Iodoformum Aromatisatum (Iodof. Arom.), Aromatized Iodoform, N.F._--Coumarin (4%) and iodoform.

_Petroxolinum Iodoformi (Petrox. Iodof.), Iodoform Petroxolin, N.F._ (Iodoform Petrox.).--An unstable preparation made from iodoform (3%), acetone, oleic acid, eucalyptol and liquid petroxolin.

_Unguentum Iodoformi (Ung. Iodof.), Iodoform Ointment, U.S.P._--Iodoform (10%) in benzoinated lard.

=*Iodum (Iodum), Iodine, U.S.P.=--I.

Epitome of the Pharmacopeia of the United States and the National Formulary Part 44

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