Epitome of the Pharmacopeia of the United States and the National Formulary Part 69

ACTION AND USES: Tannin-bearing astringent, without advantage over krameria, etc.

DOSAGE: 1 Gm. or 15 grains (N.F.).

_Fluidextractum Quercus (Fldext. Querc.), Fluidextract of Quercus, N.F._--Quercus (100%). Absolute alcohol content about 40 per cent.

DOSAGE: 1 Cc. or 15 minims (N.F.).

=Quillaja (Quillaja), Quillaja, N.F.= (Soap-tree Bark).

ACTION AND USES: Contains saponin and has been recommended as an expectorant. Similar to, but without advantage over senega. Has been used as a detergent and as an emulsifying agent; in the latter use is objectionable.

_Tinctura Quillajae (Tr. Quillaj.), Tincture of Quillaja, N.F._--Quillaja (20%) in alcohol and water. Absolute alcohol content about 30 per cent.

=Quinidina (Quinid.), Quinidine, N.F.=--An alkaloid isomeric with quinine.

White, odorless crystals or powder, with an intense and persistent bitter taste.

ACTION AND USES: At one time recommended as a cheap subst.i.tute for quinine. Inferior and obsolete.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (N.F.); antimalarial, 1 Gm. or 15 grains (N.F.) daily.

_Syrupus Quinidinae (Syr. Quinid.), Syrup of Quinidine, N.F._ (Bitterless Syrup of Quinidine).--Quinidine (3.3%) and oil of orange in syrup.

DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).

=*Quinina (Quin.), Quinine, U.S.P.=--Obtained from cinchona bark.

White, odorless, intensely bitter powder. Very slightly soluble in water (1:1560), and very soluble in alcohol (1:0.8).

ACTION AND USES: Bitter tonic, a.n.a.lgesic and antipyretic; specific against malaria. Contraindicated in ear diseases.

Idiosyncrasies are common.

The official quinine salts are more numerous than is necessary. Those that are starred would meet every indication.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).

_Oleatum Quininae (Oleat. Quin.), Oleate of Quinine, N.F._--Quinine (25%) in oleic acid.

=*Quininae Bisulphas (Quin. Bisulph.), Quinine Bisulphate, U.S.P.=--Quinine acid sulphate.

Transparent or whitish, odorless, very bitter crystals. Freely soluble in water (1:9) and soluble in alcohol (1:23).

ACTION AND USES: Similar to, and without advantage over, =Quininae Dihydrochloridum=.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).

_Tinctura Antiperiodica (Tr. Antiperiod.), Antiperiodic Tincture, N.F._ (Warburg's Tincture).--Quinine bisulphate (2%), extract of aloes (1.75%), rhubarb (0.8%), angelica fruit, elecampane, saffron, fennel, gentian, zedoary, cubeb, myrrh, camphor, agaric, pepper, Saigon cinnamon and Jamaica ginger in alcohol and water. Absolute alcohol content about 55 per cent.

USES: Antiquated, complex and irrational quinine mixture.

DOSAGE: From 4 to 15 Cc. or 1 to 4 fluidrachms (N.F.).

_Tinctura Antiperiodica sine Aloe (Tr. Antiperiod. s. Aloe), Antiperiodic Tincture without Aloes, N.F._ (Warburg's Tincture without Aloes).--The same as the preceding (Tinctura Antiperiodica) with the omission of extract of aloes.

USES AND DOSAGE: See Tinctura Antiperiodica.

=Quininae Dihydrochloridum (Quin. Dihydrochl.), Quinine Dihydrochloride, U.S.P.=

White, odorless, very bitter powder. Very soluble in water (1:0.6), and soluble in alcohol (1:12).

ACTION AND USES: Used where concentrated solutions of quinine are wanted, as for subcutaneous injections, etc.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).

=*Quininae et Ureae Hydrochloridum (Quin. et Urea. Hydrochl.), Quinine and Urea Hydrochloride, U.S.P.= (Quinine and Urea Chloride).--A double salt of quinine and urea.

Colorless, translucent crystals or white, granular powder, odorless and having a very bitter taste. Very soluble in water (1:0.9) and freely soluble in alcohol (1:2.4).

ACTION AND USES: Much less irritating than ordinary quinine salts and therefore suited for hypodermic injections, in malaria or as local anesthetic.

DOSAGE: Hypodermic, one dose daily, 1 Gm. or 15 grains (U.S.P.). For local anesthesia (hypodermic) solution of from 0.25 to 1 per cent.; (applied to mucous membranes), solutions of from 10 to 20 per cent.

=Quininae Glycerophosphas (Quin. Glycerophos.), Quinine Glycerophosphate, N.F.= (Quinine Glycerinophosphate).

Fine, white, odorless crystals or powder, with a very bitter taste.

ACTION AND USES: Expensive and superfluous quinine salt.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (N.F.); antimalarial, 1 Gm. or 15 grains (N.F.).

=Quininae Hydrobromidum (Quin. Hydrobr.), Quinine Hydrobromide, U.S.P.= (Quinine Bromide).

Light, white, odorless, very bitter silky needles. Soluble in water (1:40), and very soluble in alcohol (1:0.9).

ACTION AND USES: Superfluous; see =Quininae Hydrochloridum=.

DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.); antimalarial, at least 1 Gm. or 15 grains, daily (U.S.P.).

=*Quininae Hydrochloridum (Quin. Hydrochl.), Quinine Hydrochloride, U.S.P.= (Quinine Chloride).